辅料泊洛沙姆407的作用与应用

Effects and applications of Poloxamer 407

泊洛沙姆407是一类温度敏感型高分子材料,具有独特的反向热凝胶性质、良好的缓释作用、毒性小和生物利用度高等特点,被广泛地应用于食品与药品加工业。本文就泊洛沙姆407的结构与理化性质、作用及其机制、应用、展望等方面进行综述,以期为泊洛沙姆407的使用和进一步深度研发提供新的证据和思路。

Poloxamer 407 is a thermo-sensitive polymer material with characteristics of unique properties of reverse thermo-gel,good sustained release role,hypotoxicity and high bioavailability and so on,and is used widely in the food and pharmaceutical industry.In this paper,the structure and physical or chemical properties,effects and mechanisms,applications and outlook of Poloxamer 407 and so on are overviewed to provide new evidence and ideas for the use or further research and development of poloxamer 407.