基于选择性理论的心理干预对卵巢癌患者免疫功能的影响

Effects of psychological intervention based on selectivity theory on immune function of patients with ovarian cancer

目的探讨基于选择性理论的心理干预对卵巢癌患者免疫功能的影响。方法选取2013年12月至2016年12月确诊治疗的卵巢癌患者100例,依据干预方法分为B组和A组,每组50例。A组给予常规干预,B组在此基础上给予基于选择性理论的心理干预,统计分析所有患者干预前后心理状态、免疫功能情况。结果 B组干预后汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)得分明显低于A组,差异有统计学意义(P<0.05);B组干预后血浆T淋巴细胞亚群(CD3、CD4、CD4/CD8)水平明显高于A组,差异有统计学意义(P<0.05)。结论基于选择性理论的心理干预可有效改善卵巢癌患者的焦虑和抑郁状态,有利于改善患者免疫功能,值得临床进一步推广。

Objective To investigate the effects of psychological intervention based on selectivity theory on immune function of patients with ovarian cancer.Methods One hundred patients with ovarian cancer who were treated in our hospital from December 2012 to December 2016 were enrolled in the study.According to different intervention methods,these patients were divided into group B and group A,with 50 patients in each group.The patients in group A were treated by conventional intervention,however,the patients in group B,on the basis of group A,were treated by psychological intervention based on selectivity theory.The psychological status and immune function of patients before and after intervention were statistically analyzed and compared between two groups.Results The Hamilton anxiety scale(HAMA)scores and Hamilton depression scale(HAMD)scores after intervention in group B were significantly lower than those in group A(P<0.05).moreover the plasma levels of T lymphocyte subsets(CD3,CD4,CD4/CD8)after intervention in group B were significantly higher than those in group A(P<0.05).Conclusion The psychological intervention based on selectivity theory can effectively improve the anxiety and depression status of patients with ovarian cancer,it is helpful to improve the immune function of patients,therefor,which is worth using widely in clinical practice.