持续气道正压通气治疗对阻塞性睡眠呼吸暂停综合征合并高血压病人的血压影响及研究进展

EFFECT OF CONTINUOUS POSITIVE AIRWAY PRESSURE TREATMENT ON BLOOD PRESSURES IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME AND HYPERTENSION

高血压是引起心脑血管疾病的独立危险因素;阻塞性睡眠呼吸暂停综合征(Obstructive sleep apnea syndrome,OSAS)与心血管事件的发生及预后相关,尤其与高血压的发病密切相关。持续气道正压通气(continuous positive airway pressure,CPAP)可有效阻止上气道阻塞和低氧血症的发生,改善OSAS病人的临床症状,但作为OSAS的首选治疗方法,其对OSAS伴高血压病人的血压降低情况仍未得到具体的肯定。本文对目前在国内外经CPAP辅助治疗对高血压合并阻塞性睡眠呼吸暂停综合征病人血压的治疗效果进行分析。

Hypertension is an independent risk factor for cardiovascular and cerebrovascular diseases.Obstructive sleep apnea syndrome(OSAS)is associated with the occurrence and prognosis of cardiovascular events,especially with the pathogenesis of hypertension.Continuous positive airway pressure(CPAP)can effectively prevent the occurrence of upper airway obstruction and hypoxemia,and improve the clinical symptoms of OSAS patients.However,as the preferred method for treatment of OSAS,the reduction of blood pressure in patients with OSAS and hypertension is still not given specific affirmation.This article analyzes the effect of CPAP adjuvant therapy at home and abroad on blood pressure in patients with hypertension and obstructive sleep apnea syndrome.