老年慢阻肺患者合并肺部感染的病原体研究

Pathogens of Pulmonary Infection in Elderly Patients with Chronic Obstructive Pulmonary Disease

目的观察并研究老年慢阻肺合并肺部感染患者的病原体情况。方法方便选择2016年11月—2017年10月该院接诊的300例老年慢阻肺患者合并肺部感染患者作为该次研究对象,对患者痰液标本进行病原菌培养及菌型临床分析鉴定。结果 300例老年慢阻肺合并肺部感染患者中痰液标本培养阳性有130例,检出率为43.33%;其中病原体检出株数为139株,真菌13例(9.35%)、革兰阳性菌8例(5.75%)、革兰阴性菌118例(84.89%)。结论老年慢阻肺合并肺部感染患者主要病原菌是革兰阴性菌,因此,应制定以治疗革兰阴性杆菌为主的联合方案,同时需重点防范耐药性真菌及金黄色葡萄球菌感染。

Objective This paper tries to observe and study the pathogens in elderly patients with COPD and pulmonary infection.Methods 300 cases of elderly COPD patients with pulmonary infection from November 2016 to October 2017 in the hospital were convenient selected and regarded as the object of this study.The patient sputum specimens for pathogenic bacteria culture and clinical analysis were identified.Results Among 300 elderly patients with COPD and pulmonary infection,sputum samples were cultured in 130 cases with the detection rate of 43.33%.Among them,139 strains were detected,13 were fungi(9.35%),8 were Gram-positive bacteria cases(5.75%),Gram-negative bacteria in 118 cases(84.89%).Conclusion Gram-negative bacteria should be the main pathogens in elderly patients with chronic obstructive pulmonary disease and pulmonary infection.Therefore,a merger of antibiotic-resistant fungi and Staphylococcus aureus should be given priority to in combination with Gram-negative bacilli.