评估强化降糖治疗对急性心肌梗塞(AMI)合并2型糖尿病(DM)患者改善心功能及预后的价值

Evaluation of the Value of Intensive Hypoglycemic Therapy in Improving Cardiac Function and Prognosis in Patients with Acute Myocardial Infarction(AMI) and Type 2 Diabetes Mellitus(DM)

目的研究强化降糖治疗对急性心肌梗塞合并2型糖尿病患者改善心功能以及预后的影响。方法方便选取2015年3月—2016年12月在该院接受诊治的将86例急性心肌梗塞合并2型糖尿病患者视为研究对象,并分为对照组和研究组,各43例。研究组血糖控制在4.5~6.0 mmol/L内,对照组血糖控制在6.1~11.0 mmol/L内。治疗前、后比较两组患者的心功能指标和血糖指标的变化情况。结果治疗前,两组患者的心功能指标和血糖指标差异无统计学意义(P>0.05)。治疗后,两组的血糖和心功能均得以改善,对照组的Hb Alc为(6.24±0.45)%,研究组为(5.06±0.35)%,(P=0.01);研究组的hs-CRP为(5.16±2.34)mg/L,对照组为(7.35±1.54)mg/L,(P=0.03);对照组的LVD为(46.37±3.45)mm,研究组为(42.26±2.25)mm,(P=0.02);研究组的LVEF为(57.34±3.53)%,对照组为(51.25±2.36)%,(P=0.04)。结论强化降糖治疗可明显改善心肌梗塞合并2型糖尿病患者的心功能,患者的血糖得到良好控制,预后良好。

Objective This paper tries to investigate the effects of intensive hypoglycemic therapy on improving cardiac function and prognosis in patients with acute myocardial infarction and typeⅡdiabetes mellitus.Methods A total of 86 patients with acute myocardial infarction complicated with type 2 diabetes treated in this hospital from March 2015 to December 2016 were convenient selected as the study subjects and divided into control group and study group,with 43 cases in each group.The study group blood glucose control in 4.5~6.0 mmol/L,the control group blood glucose control in 6.1~11.0 mmol/L within.Before and after treatment,the changes of cardiac function and blood glucose in two groups were compared.Results Before treatment,there was no significant difference in cardiac function index and blood glucose index between the two groups(P>0.05).After treatment,the blood glucose and heart function of the two groups were all improved.The HbAlc of the control group was(6.24±0.45)%,the study group was(5.06±0.35)%,(P=0.01).The hs-CRP of the study group was(5.16±2.34)mg/L,the control group was(7.35±1.54)mg/L,(P=0.03).The LVD of the control group was(46.37±3.45)mm,the study group was(42.26±2.25)mm(P=0.02).The study group’s LVEF was(57.34±3.53)%,while the control group was(51.25±2.36)%(P=0.04).Conclusion Strengthening hypoglycemic therapy can significantly improve the cardiac function of myocardial infarction complicating type 2 of diabetes mellitus patients,the blood glucose was well controlled,the prognosis was good.