血清不规则抗体检测在输血工作中的临床效果分析

Clinical Analysis of Serum Irregular Antibody in Transfusion

目的探讨在输血工作中应用血清不规则抗体检测的临床效果。方法应用随机数字法,从该院2016年8月—2017年8月接收的输血患者中方便抽取340例作为该次研究的对象,所有患者均在输血前先展开血清不规则抗体检测,观察其结果。结果 (1)阳性不规则抗抗体共3例,检出率是0.88%。其余337例均为阴性患者,比例是99.12%,阴性与阳性检出率对比差异有统计学意义(P<0.05)。(2)3例阳性患者中,2例患者为Rh系统抗体阳性,比例是66.67%,包括了抗-E抗体与抗-DC抗体各1例;另外1例为MNS系统抗-M抗体阳性,所占比例是33.33%,比较差异有统计学意义(P<0.05)。结论在输血工作中采取抗人球蛋白法进行血清不规则抗体检测,能够提升检出率的准确性,明确患者的不规则抗体类型,能够提升临床输血效果,值得推广与使用。

Objective This paper tries to discuss the clinical effect of detecting serum irregular antibody in blood transfusion.Methods Randomized digital method was conveniently selected 340 cases of transfusion patients from August 2016 to August 2017 in this hospital.All patients were tested for irregular serum antibodies before observing the transfusion results.Results①A total of 3 positive anti-anti-body antibodies,the detection rate was 0.88%.The remaining 337 cases were negative patients,the proportion was 99.12%,negative and positive detection rate was statistically significant(P<0.05).②Of 3 positive patients,2 were positive for Rh system antibody,the ratio was 66.67%,including 1 anti-E antibody and anti-DC antibody;the other 1 was positive for MNS system anti-M antibody,the proportion was 33.33%,which was statistically significant(P<0.05).Conclusion In the blood transfusion to take anti-human globulin method to detect irregular serum antibodies,can improve the accuracy of the detection rate,identify patients with irregular antibody types,can enhance clinical transfusion,it is worth promoting and use.