盐酸溴己新葡萄糖注射液佐治小儿下呼吸道感染52例效果分析

Analysis of Effect of Bromhexin Hydrochloride Injection in Adjunctive Treatment of 52 Cases of Children with Lower Respiratory Tract Infection

目的探讨盐酸溴己新葡萄糖注射液佐治52例小儿下呼吸道感染的临床疗效。方法方便选取该院2015年7月—2016年2月期间所收治的52例下呼吸道感染患儿作为该次研究病例,按照治疗方法的不同将其分为研究组和对照组,对照组采取常规治疗,研究组在此基础上加用盐酸溴己新葡萄糖注射液治疗,对比分析两组患儿的临床疗效,并观察两组患儿咳喘好转时间、肺喘鸣音消失时间与肺湿性啰音消失时间和住院时间。结果研究组治愈率为61.54%,显著高于对照组38.46%,且研究组治疗总有效率(92.31%)明显高于对照组(65.38%),组间差异有统计学意义(χ~2=5.649 7,P=0.017 4);研究组咳喘好转时间、肺喘鸣音消失时间、肺湿性啰音消失时间明显少于对照组,且研究组住院时间为(7.03±1.18)d,与对照组(10.21±2.09)d相比较少,两组之间差异有统计学意义(t=4.805 7,3.292 7,3.6146,6.755 9,P<0.05)。结论盐酸溴己新葡萄糖注射液治疗小儿下呼吸道感染的效果显著,能够有效改善患儿的临床症状,缓解患儿的炎症反应,值得临床应用。

Objective To study the clinical curative effect of bromhexin hydrochloride injection in adjunctive treatment of 52 cases of children with lower respiratory tract infection.Methods 52 cases of children with lower respiratory tract infection admitted and treated in our hospital from July 2015 to February 2016 were conveniently selected and divided into two groups according to different treatment methods,the control group used the routine therapy,while the research group used the bromhexin hydrochloride injection on the basis of the control group,and the clinical curative effect was compared between the two groups,and the improvement time of cough,lung wheezes disappearance time,lung moist rale disappearance time and length of stay of the two groups were observed.Results The cure rate in the research group was obviously higher than that in the control group(61.54%vs 38.46%),and the total treatment effective rate in the research group was obviously higher than that in the control group(92.31%vs 65.38%),and the difference was statistically significant(χ2=5.649 7,P=0.017 4),and the improvement time of cough,lung wheezes disappearance time,lung moist rale disappearance time in the research group were obviously lower than those in the control group,and the length of stay in the research group was shorter than that in the control group[(7.03±1.18)d vs(10.21±2.09)d],and the difference was statistically significant(t=4.805 7,3.292 7,3.614 6,6.755 9,P<0.05).Conclusion The effect of bromhexin hydrochloride injection in adjunctive treatment of lower respiratory tract infection is obvious,which can effectively improve the clinical symptoms and relieve the inflammatory reactions,and it is worth clinical application.