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自拟安神解郁汤加味治疗重度失眠所致抑郁的疗效探讨

Study on Curative Effect of Self-made Anshen Jieyu Tang Jiawei in Treatment of Depression Caused by the Severe Insomnia
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摘要 目的观察自拟安神解郁汤加味治疗重度失眠所致抑郁的疗效,为临床治疗提供借鉴。方法方便选取2015年1月—2017年6月间该院收治的74例重度失眠所致抑郁患者,按照随机分组方式分为对照组(n=37)和观察组(n=37),对照组给予精神药品配合其它中成药治疗,观察组给予精神药品加用自拟安神解郁汤加味治疗,疗程均为6周,然后对比两组患者的临床治疗效果。结果对照组患者的睡眠质量指数为(13.82±2.24)分,而观察组为(9.67±1.85)分,显著优于对照组(t=7.239,P<0.05);对照组患者的抑郁自评量表得分为(58.72±6.94)分,而观察组为(47.67±5.75)分,显著优于对照组(t=5.008,P<0.05);对照组患者的焦虑自评量表得分为(57.64±6.52)分,而观察组为(45.39±5.48)分,显著优于对照组(t=5.735,P<0.05);对照组患者的治疗总有效率为67.57%(25/37),而观察组为91.89%(34/37),显著高于对照组(χ~2=6.773,P<0.05)。结论自拟安神解郁汤加味治疗重度失眠所致抑郁具有显著疗效,可有效调养患者情志,发挥镇静催眠作用,改善患者的失眠和抑郁症状,值得在临床治疗中推广应用。 Objective To observe the curative effect of self-made anshen jieyu tang jiawei in treatment of depression caused by the severe insomnia and provide reference for clinical treatment.Methods 74 cases of patients with depression caused by the severe insomnia admitted and treated in our hospital from January 2015 to June 2017 were convenient selected and randomly divided into two groups with 37 cases in each,the control group used the mental drugs and other TCM drugs for treatment,while the observation group used the mental drugs and self-made anshen jieyu tang jaiwei for treatment,and the treatment course was six weeks,and then the clinical treatment effect was compared between the two groups.Results The sleep quality index in the observation group was obviously better than that in the control group,[(9.67±1.85)points vs(13.82±2.24)points](t=7.239,P<0.05);the depression self-evaluation scale score in the observation group was obviously better than that in the control group,[(47.67±5.75)points vs(58.72±6.94)points](t=5.008,P<0.05);the anxiety self-evaluation scale score in the observation group was obviously better than that in the control group,[(45.39±5.48)points vs(57.64±6.52)points](t=5.735,P<0.05);the total effective rate in the observation group was obviously higher than that in the control group,[91.89%(34/37)vs 67.57%(25/37)](χ2=6.773,P<0.05).Conclusion The curative effect of self-made anshen jieyu tang jiawei in treatment of depression caused by the severe insomnia is obvious,which can effectively adjust the emotion of patients,give play to the role of sedation and improve the symptoms of insomnia and depression,and it is worth promotion and application in clinical treatment.
作者 刘兴华 LIU Xing-hua(Department of TCM,Beipiao Central Hospital,Beipiao,Liaoning Province,122100 China)
出处 《中外医疗》 2018年第8期166-168,共3页 China & Foreign Medical Treatment
关键词 自拟安神解郁汤 加味 重度 失眠 抑郁 Self-made anshen jieyu tang Jiawei Severe Insomnia Depression
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