冠心病给予瑞舒伐他汀与阿托伐他汀治疗的临床效果比较

Comparison of the clinical effects of rosuvastatin and atorvastatin in the treatment of coronary heart disease

目的:探讨冠心病患者接受瑞舒伐他汀与阿托伐他汀治疗的疗效差异。方法:收治冠心病患者82例,随机分为对照组和观察组。观察组采用瑞舒伐他汀治疗,对照组采用阿托伐他汀治疗,比较两组治疗效果。结果:治疗后,观察组总胆固醇、低密度脂蛋白胆固醇、甘油三酯、高密度脂蛋白胆固醇、超敏C-反应蛋白水平均显著优于对照组(P<0.05)。两组不良反应发生率差异无统计学意义(P>0.05)。结论:相较于阿托伐他汀,瑞舒伐他汀对冠心病患者降血脂效果更好,患者炎性指标改善更明显。

Objective:To explore the difference of curative effect of rosuvastatin and atorvastatin in the treatment of coronary heart disease.Methods:82 patients with coronary heart disease were selected.They were randomly divided into the control group and the observation group.The observation group was treated with rosuvastatin,and the control group was treated with atorvastatin.We compared the therapeutic effect of two groups.Results:After treatment,the total cholesterol,low density lipoprotein cholesterol,three acylglycerol,high-density lipoprotein cholesterol and high sensitivity C-reactive protein levels in the observation group were significantly better than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between groups(P>0.05).Conclusion:Compared with atorvastatin,the effect of rosuvastatin on reducing blood lipid in patients with coronary heart disease was better,and the improvement of inflammatory index was more obvious in patients.