摘要
龋病是一种以细菌为主的多因素作用下,牙体硬组织发生慢性进行性破坏的疾病。根据生态菌斑学说,龋病的发生不是单一致病菌作用的结果,而是口腔生态平衡失调的结果。益生菌作为调节菌群微生态系统的一类健康菌群,可与变形链球菌产生相关拮抗作用,分泌相应抑菌代谢产物,抑制其生长繁殖,减少唾液中变形链球菌数量,从而预防龋病。因此益生菌可能对龋病的预防起积极作用,在促进人类口腔健康中扮演重要角色。
Dental caries,a chronic infectious disease,is a breakdown of teeth due to activities of bacteria.According to the ecological plaque theory,the occurrence of caries is not the result of single pathogenic bacteria,but the result of oral ecologic imbalance.Probiotics are a kind of healthy bacteria that regulate the oral microecosystem.It can produce antagonism with Streptococcus mutans,secrete corresponding metabolites,inhibit the growth and reproduction of Streptococcus mutans and reduce the number of Streptococcus mutans in saliva.Therefore probiotics may play an active role in the prevention of dental caries and an important role in promoting human oral health.
作者
马婧娴
李艳红
MA Jingxian;LI Yanhong(Department of Oral Prevention,Stomatology Hospital Affiliated to Kunming Medical University,Kunming 650106,China)
出处
《医学综述》
2018年第8期1493-1497,共5页
Medical Recapitulate
基金
云南省科技厅-昆明医科大学应用基础研究联合专项(2017FE468[-233])
关键词
龋病
益生菌
乳杆菌
变形链球菌
Caires
Probiotic
Lactobacillus
Streptococcus mutans
