寨卡病毒相关研究现状

Research status of Zika virus

寨卡病毒为一种虫媒传播病毒,于1947年首次被人们发现。人感染寨卡病毒后的临床表现主要为皮疹、低热、关节痛或结膜炎。但该病毒也可导致严重的并发症,如小头畸形、吉兰-巴雷综合征、睾丸损伤及眼部病变等。世界卫生组织于2016年11月宣布,将寨卡病毒疫情视为需要采取紧急行动的持续挑战。目前尚无针对寨卡病毒感染的特效药物上市,临床上主要采取休息、补液等对症治疗。疫苗为预防寨卡病毒感染及复燃的重要手段,并已进入临床试验阶段。

Zika virus is an insect-borne virus which was first discovered in 1947.The clinical manifestations of human infection with Zika virus mainly include skin rash,low fever,joint pain and conjunctivitis.However,the virus can also cause serious complications,such as microcephaly,Guillain-Barrés syndrome,testicular damage and eye lesions.In November 2016,the World Health Organization announced that urgent action was needed to the Zika virus outbreak as a continuing challenge.At present,symptomatic treatment such as rest and rehydration are mainly adopted for Zika virus infection,and no specific drug is available.The vaccine is an important means to prevent the infection and reactivation of Zika virus and has entered the clinical trial stage.