非小细胞肺癌的淋巴结转移规律及影响因素

Lymph node metastasis and its influencing factors in non-small cell lung cancer

肺癌目前是全世界与癌症相关死亡的最常见原因,非小细胞肺癌(NSCLC)占所有肺癌的85%,其淋巴结转移多数是按肺内淋巴结到肺门淋巴结再到纵隔淋巴结的顺序进行逐级转移,但也有其他转移路径,而肿瘤的原发部位、肿瘤大小、肿瘤标志物与NSCLC的淋巴结转移有密切关系,本文综述了NSCLC淋巴结转移规律及影响因素,旨在为临床治疗选择提供参考,从而提高肺癌患者的生存率、降低复发率和转移率。

Lung cancer is currently the most common cause of cancer-related death worldwide.Non-small cell lung cancer(NSCLC)accounts for 85%of all lung cancer.Its lymph node metastases mostly take the route from intrapulmonary lymph nodes to hilar lymph nodes to mediastinal lymph nodes step by step,but there are also other metastatic path.The primary tumor site,tumor size,and tumor biomarkers are closely related to NSCLC lymph node metastasis.This paper reviews the NSCLC lymph node metastasis route and its influencing factors,in order to provide reference for the selection of clinical treatment,to improve the survival rate of lung cancer,and to lower recurrence rate and metastasis rate.