球囊扩张式支架治疗症状性颅内动脉狭窄的临床应用

Clinical study of balloon-expand-able stent treatment for symptomatic intracranial arterial stenosisin at perioperative period

目的探讨球囊扩张式支架治疗症状性颅内动脉粥样硬化性狭窄围手术期的安全性及有效性。方法分析药物治疗无效而选择球扩式支架置入治疗的颅内动脉重度狭窄患者38例临床和影像学资料,分析颅内动脉狭窄形态、技术成功率、围手术期并发症、临床及影像随访结果。结果 1)本组患者支架成形术的技术成功率为97.36%,术后平均狭窄率(88.27±5.242)%下降至(11.24±4.36)%;2)所有患者进行30天围手术期随访观察,其中1例术中发生蛛网膜下腔出血,1例术中急性支架内血栓形成。结论球扩式支架治疗重度症状性颅内动脉粥样硬化性狭窄的技术成功率高,治疗相对安全,短期疗效较好。

Objective To explore the safety and efficacy of balloon-expand-able stent treatment for symptomatic intracranial arterial stenosis in a 30-day perioperative period.Methods The clinical and imaging data of 38 patients of high-grade intracranial arterial stenosis who were ineffectiveness of drug from September 2015 to August 2017 were analyzed retrospectively.The status of intracranial arterial stenosis,technical success rate,perioperative complications and clinical and imaging follow-up were analyzed.Results The technical success rate of stents in this group was 97.36%,and the average rate of stenosis(88.27±5.24)%decreased to(11.24±4.36)%after surgery.All patients were followed a 30 days of perioperative observation,among whom one got subarachnoid hemorrhage,and another one had acute stent thrombosis during the operation.Conclusion The balloon-expand-able stent treatment for high-grade symptomatic intracranial arterial stenosis is relatively safe,with high successful rate and better short-term efficacy.