枯草芽孢杆菌中性蛋白酶的研究进展

Research advances in the neutral protease of Bacillus subtilis

中性蛋白酶因作用条件温和广泛应用于食品、医药以及饲料等领域。枯草芽孢杆菌为肠道益生菌,且具有较强的蛋白酶活性而受到极大关注。该文对枯草芽孢杆菌中性蛋白酶的特性与应用、提高枯草芽孢杆菌中性蛋白酶活力的途径以及枯草芽孢杆菌中性蛋白酶的分离纯化方法进行了综述,并对存在的问题进行了分析与展望,旨在为枯草芽孢杆菌产中性蛋白酶的深入研究提供参考。

Neutral protease is widely used in food,medicine,feeds and other fields due to their mild conditions.As a probiotic bacterium in the intestinal tract,Bacillus subtilis has strong protease activity and gets a lot of attention.The characteristics and application of neutral protease of B.subtilis,the ways to improve the activity of neutral protease of B.subtilis and the separation and purification of neutral protease from B.subtilis were reviewed.Subsequently,the current existing problems were analyzed and prospected,aiming to provide reference for further study of protease production by B.subtilis.