小切口甲状腺切除术联合甲磺酸阿帕替尼在甲状腺瘤患者中的临床效果分析

The Effects of Small Incisional Thyroidectomy Combined with Apatinib on Patients with Thyroid Tumor

目的探讨小切口甲状腺切除术联合甲磺酸阿帕替尼在甲状腺瘤患者中的临床应用效果及对血清肿瘤特异性生长因子的影响。方法选取我院收治的甲状腺瘤患者100例,随机分为两组,对照组应用小切口甲状腺切除术,研究组使用小切口甲状腺切除术联合甲磺酸阿帕替尼进行治疗,对比两组患者临床效果以及对血清肿瘤特异性生长因子的影响。结果治疗后研究组患者的临床疗效显著优于对照组(P<0.05);研究组患者的血清肿瘤特异性生长因子水平明显低于对照组(P<0.05);研究组患者的生活质量明显优于对照组(P<0.05);研究组患者的疾病控制率明显优于对照组(P<0.05)。结论应用小切口甲状腺切除术联合甲磺酸阿帕替尼治疗甲状腺瘤患者的临床效果显著,对患者的血清肿瘤特异性生长因子具有一定影响,安全性较高,值得在临床推广及应用。

Objective To investigate the clinical application effect of small incision thyroidectomy combined with apatinib mesylate on patients with thyroid tumor and its effect on serum tumor-specific growth factor.Methods 100 patients with thyroid adenoma in our hospital were randomly divided into control group and research group.The patients in control group were given small incision thyroid resection,while the patients in research group were given small incision thyroid resection combined with apatinib mesylate for treatment.The clinical effect and its influence on serum tumor specific growth factor of patients between the two groups were compared.Results The clinical efficacy of patients in the treatment group was significantly better than in the control group(P<0.05).The serum tumor specific growth factor of patients in the research group was significantly lower than in the control group(P<0.05).The quality of life of the patients after treatment was significantly better in the research group than in the control group(P<0.05).The disease control rate of the patients after treatment was significantly higher in the research group than in the control group(P<0.05).Conclusion The small incision thyroidectomy combined with apatinib mesylate had great clinical effect on patients with thyroid adenoma.This treatment had high security,and was worth clinical promotion and application.