青年肺癌与老年肺癌手术患者的临床病理特征对照

Comparison of clinicopathologic features of youth lung cancer and senile lung cancer surgical patients

目的:对比青年肺癌与老年肺癌手术患者的临床病理特征。方法:选取青年肺癌与老年肺癌手术患者各50例,分别为本研究的青年组和老年组,分析比较两组患者的临床病理特点。结果:青年组患者病理类型以腺癌为主,比例明显多于老年组;青年组患者TNM分期主要为Ⅲb-IV期,老年组患者TNM分期主要为Ⅰ-Ⅲa期,组间差异有显著统计学意义(P<0.01);青年组患者治疗方式以全肺切除为主,而老年组则以肺叶切除方式为主,差异有显著统计学意义(P<0.01);两组5年生存率差异无统计学意义(P>0.05)。结论:青年肺癌患者和老年肺癌患者相比,临床症状表现复杂但无特异性,早期容易误诊。患病后青年患者的病情往往发展迅速,手术治疗效果不理想且治疗预后较差。因此,需要通过各种诊断方式综合分析患者的病情,根据其具体情况合理选择正确的治疗方式,提高青年肺癌确诊率和生存率,改善疾病的治疗效果,提高患者的生存质量和生命安全。

Objective:To compare clinicopathologic features of youth lung cancer and senile lung cancer surgical patients.Methods:50 cases of youth lung cancer and 50 cases of senile lung cancer were selected as youth group and senile group,respectively.The clinicopathologic features of the two groups were analyzed and compared.Results:The pathology type of the youth group was mainly adenocarcinoma,which was significantly more than that of the senile group.The TNM staging of the youth group was mainly I-IIIa stage,which was more than that of the elderly group,and the difference was statistically significant(P<0.01).The treatment method of the youth group was mainly pneumonectomy;however,the elderly group was mainly pulmonary lobectomy,and the difference was statistically significant(P<0.01).Further,the differences in the death rate were not statistically significant between the two group(P>0.05).Conclusions:Compared with senile lung cancer patients,the youth lung cancer patients have complicated but not specific clinical symptoms,so,it is easy to be misdiagnosed at early stage.Further,the conditions of the youth patients usually develop rapidly,the surgical results are unsatisfactory and the prognosis is worse.Therefore,the conditions of the youth patients should be analyzed by various diagnosis methods,and the therapy methods should be chosen according to the specific circumstances in order to improve confirmed diagnostic rate and survival rate of them,and improve treatment effects,life quality and life safety.