针刺大陵穴对大鼠踝部软组织损伤血液流变的影响

Effect of Acupuncture at Daling(P7) on the Hemorrheology of Soft Tissue Injury in the Ankle of Rats

目的研究针刺大陵穴对大鼠踝部软组织损伤血液流变的影响,探讨其活血化瘀止痛机制。方法造模成功后将大鼠随机分为空白对照组、常规针刺组及平衡针刺组,每组31只。分别进行不治疗、常规针刺及平衡针刺等方法干预。每天1次,连续治疗21 d。实验后测定全血黏度、血浆黏度、红细胞聚集指数等指标。结果治疗后肉眼及外表评分,平衡针刺组与常规针刺组及空白对照组比较都有非常显著性差异(P<0.01),常规针刺组与空白对照组无显著性差异(P>0.05);治疗后血流变,平衡针刺组与其它2组比较,全血黏度显著降低(P<0.05或P<0.01),血浆黏度、纤维蛋白原都显著性减少(P<0.01),红血细胞压积、红细胞聚集指数明显升高(P<0.01)。结论平衡针刺大陵穴,外观上能够更好地减轻皮下瘀血,活血消肿,实验检查显示改善血流变各项指标。

Objective To study the effect of acupuncture at Daling(P7)on the hemorrheology of soft tissue injury in the ankle of rats,and to explore the mechanism of activating blood to dissipate blood stasis and relieve pain.Methods The rats were randomly divided into the blank control group,the control group and the treatment group,with 31 rats in each group.They were treated without treatment,routine acupuncture and balanced acupuncture one time a day for 21 days.The whole blood viscosity,plasma viscosity and erythrocyte aggregation index were measured after the experiment.Results Comparing with naked eye and appearance scores in each group after treatment,the balance acupuncture group and conventional acupuncture group and control group had significant differences(P<0.01),and conventional acupuncture group and blank control group had no significant difference(P>0.05).After treatment,blood rheology and its balance and the whole blood viscosity significantly decreased(P<0.05 or P<0.01),plasma viscosity and fibrinogen were significantly reduced(P<0.01),hematocrit,erythrocyte aggregation index increased significantly(P<0.01).Conclusion The acupuncture at Daling(P7)can reduce the subcutaneous ecchymosis and the swelling of blood,and the experimental examination showed the improvement of blood rheology.