摘要
岩藻糖是肠道上皮细胞黏蛋白糖基化的重要糖基,可以作为肠道微生物的能量物质,参与肠道微生物的黏附、定植以及免疫调节,对于促进肠道微生物稳态,维持肠道健康有重要作用。本文主要对岩藻糖基化过程,岩藻糖在肠道中的积极调控作用以及肠道微生物、免疫细胞对岩藻糖表达的诱导进行综述,以期为维持肠道微生物稳态和肠道健康提供新的参考。
Fucose is an important sugar group of fucosylation in intestinal epithelial cells.As an energy source for gut microbiota,fucose is involved in the adhesion,planting and immune regulation of microbiota,which plays an important role in promoting gut microbial homeostasis and keeping intestine health.In this review,we elucidated the process of fucosylation,constructive regulatory roles of fucose in gut microbiota,induction of intestinal microbiota and immune cells on fucosylation,which potentially provided theoretical foundation for improving the homeostasis of intestinal microbiota and health of intestine.
作者
张晓音
赵圣国
骆超超
郑楠
王加启
ZHANG Xiaoyin;ZHAO Shengguo;LUO Chaochao;ZHENG Nan;WANG Jiaqi(Key Laboratory of Quality and Safety Control for Milk and Dairy Products of Ministry of Agriculture,Institute of Animal Sciences,Chinese Academy of Agricultural Sciences,Beijing 100193,China;Laboratory of Quality and Safety Risk Assessment for Dairy Products of Ministry of Agriculture(Beijing),Institute of Animal Sciences, Chinese Academy of Agricultural Sciences,Beijing 100193,China;State Key Laboratory of Animal Nutrition,Institute of Animal Sciences,Chinese Academy of Agricultural Sciences, Beijing 100193,China;College of Animal Science and Technology, Huazhong Agricultural University,Wuhan 430070,China)
出处
《动物营养学报》
CAS
CSCD
北大核心
2018年第7期2473-2479,共7页
CHINESE JOURNAL OF ANIMAL NUTRITION
基金
国家重点研发计划(2017YFD0500502)
现代农业产业技术体系(CARS-36)
中国农业科学院科技创新工程(ASTIP-IAS12)。
