免疫组化指标在宫颈微偏腺癌诊断中的应用

Application of Immunohistochemical Markers in Diagnosis of Minimal Deviationadenocarcinoma of Cervix

宫颈微偏腺癌(MDA)是一种原发于宫颈的特殊类型腺癌,发病率较低。虽然肿瘤细胞分化很好,但是该种肿瘤患者预后极差。由于缺乏恶性细胞学特征,细胞学检查(TCT)几乎无法做出诊断;且由于活检组织标本较小、腺体形态及结构均类似于正常宫颈腺体,活检病理检查也极易漏诊。近年来多项免疫组化指标的联合应用有助于对MDA做出正确的病理诊断,本文对这些免疫组化指标在宫颈微偏腺癌中的应用进行了归纳总结。

Minimal deviationadenocarcinoma of cervixis(MDA)a type of adenocarcinoma of primary origin in the cervix with a low incidence.Although tumor cells differentiate well,the prognosis of this tumor patient is extremely poor.Due to the lack of malignant cytological features,cytology tests(TCT)can hardly make a diagnosis;and because biopsy tissue specimens are small,glandular morphology and structure are similar to normal cervical glands,biopsy pathological examination is also easily missed.In recent years,the combined use of multiple immunohistochemical markers has contributed to the correct pathological diagnosis of MDA.The application of these immunohistochemical markers in cervical minimal deviation adenocarcinoma is summarized in this paper.