老年脑卒中后抑郁及血管性认知功能障碍的研究分析

Analysis of Post-stroke Depression and Vascular Cognitive Impairment in Elderly Patients

目的探讨老年卒中患者的抑郁障碍及血管性认知功能障碍发生情况,并进一步研究卒中患者抑郁障碍与血管性认知功能障碍的关系。方法随机选取我院2016年1月~2017年8月治疗的204例老年卒中患者,采用汉密尔顿抑郁量表、蒙特利尔认知评估量表和简明精神状态检查量表对卒中患者进行评估,观察患者抑郁障碍发生率、血管性认知功能障碍、HAMD得分、MoCA得分及MMSE得分情况。结果老年卒中患者的抑郁障碍发生率为52.45%,不同年龄间的抑郁障碍发生率,差异有统计学意义(P<0.05);抑郁障碍患者的血管性认知功能障碍的发生率,高于非抑郁障碍患者(P<0.05);不同程度的抑郁障碍患者发生血管性认知功能障碍,差异有统计学意义(P<0.05);卒中患者的HAMD得分与MoCA得分及MMSE得分呈负相关(P<0.05)。结论老年卒中患者的抑郁障碍及血管性认知功能障碍发病率较高,抑郁障碍的发生对血管性认知功能障碍的发生具有一定影响。

Objective To investigate the incidence of depressive disorder and vascular cognitive impairment in elderly patients with stroke,and to further study the relationship between depressive disorder and vascular cognitive impairment in stroke patients.Methods A total of 204 elderly patients with stroke who were treated in our hospital from January 2016 to August 2017 were randomly selected and assessed by the Hamilton Depression Scale,Montreal Cognitive Assessment Scale,and Concise Mental State Examination Scale.The patients were observed for depression.Incidence of disorders,vascular cognitive impairment,HAMD score,MoCA score,and MMSE score.Results The incidence of depressive disorder in elderly patients with stroke was 52.45%,and the incidence of depressive disorder in different ages was statistically significant(P<0.05);the incidence of vascular cognitive impairment in depressive patients was higher than that of non depressive disorder patients(P<0.05);vascular cognitive work in patients with different degrees of depressive disorder occurred,the difference was statistically significant(P<0.05);the HAMD score of stroke patients was negatively correlated with MoCA score and MMSE score(P<0.05).Conclusion The incidence of depressive disorder and vascular cognitive impairment in elderly patients with stroke is higher,and the occurrence of depressive disorder has a certain influence on the occurrence of vascular cognitive impairment.