溶栓后PCI与pPCI治疗急性ST段抬高型心肌梗死的临床效果研究

Clinical Effect of PCI and pPCI on Acute ST Segment Elevation Myocardial Infarction after Thrombolysis

目的研究溶栓后PCI和pPCI两种技术治疗急性ST段抬高型心肌梗死的临床效果。方法选择我院收治的急性ST段抬高型心肌梗死患者86例,随机分为对照组和治疗组,每组43例。对照组采用pPCI方式治疗,治疗组采用溶栓后PCI方式治疗。观察两组患者的治疗有效率、不良反应、心功能指标(LVEF、LVEDd)、心肌梗死症状消失时间、心功能指标恢复正常时间、临床治疗总时间等临床指标。结果治疗组治疗总有效率为90.70%,优于对照组的72.09%,差异具有统计学意义(P<0.05)。治疗组不良反应发生1例,少于对照组的7例,差异具有统计学意义(P<0.05)。治疗前后LVEF、LVEDd的改善幅度大于对照组,心肌梗死症状消失时间、心功能指标恢复正常时间、临床治疗总时间均短于对照组,差异具有统计学意义(P<0.05)。结论溶栓后经皮冠状动脉介入技术治疗急性ST段抬高型心肌梗死,能够提高治疗效果,改善心功能,缩短恢复时间,减少不良反应。

Objective To study the clinical effect of two kinds of PCI and pPCI after thrombolytic therapy in the treatment of acute ST segment elevation myocardial infarction.Methods 86 patients with acute ST-elevation myocardial infarction admitted to our hospital were randomly divided into control group and treatment group,43 cases in each group.The control group was treated with pPCI,and the treatment group was treated with thrombolytic PCI.Observe the clinical indicators such as treatment efficacy,adverse reactions,heart function indexes(LVEF,LVEDd),disappearance time of myocardial infarction symptoms,normal time of cardiac function indexes,and total clinical treatment time for the two groups of patients.Results The total effective rate of the treatment group was 90.70%,which was better than the 72.09%of the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the treatment group was 1 case,and less than 7 cases in the control group,the difference was statistically significant(P<0.05).The improvement of LVEF and LVEDd before and after treatment was greater than that of the control group.The disappearance of myocardial infarction symptoms,the restoration of normal heart function,and the total clinical treatment time were all shorter than those of the control group,the difference was statistically significant(P<0.05).Conclusion Percutaneous transcatheter coronary intervention after thrombolysis in the treatment of acute ST segment elevation myocardial infarction can improve the therapeutic effect,improve cardiac function,shorten recovery time,and reduce adverse reactions.