舒芬太尼经鼻给药与静脉给药在纤维结肠镜检查中疗效对比

Comparison of Efficacy of Sufentanil between Nasal and Intravenous Administration in Fibrocolonoscopy

目的探究经鼻与经静脉的不同舒芬太尼给药方式应用在纤维肠镜的检查期间的临床效果。方法选取2016年7月~2017年7月我院收治的62例患者的临床资料,依据给药方式分为对照组与研究组,每组31例。对照组行舒芬太尼静脉给药,研究组行舒芬太尼鼻滴给药,分析两组生命指标与临床指标。结果研究组的心率与MAP低于对照组,Sp O2高于对照组,差异有统计学意义(P<0.05);研究组的临床指标相比对照组指标优,差异有统计学意义(P<0.05)。结论纤维肠镜在检查时经鼻使用舒芬太尼临床效果更好,患者生命体征稳定,药物对呼吸抑制功能弱,有临床推广价值。

Objective To investigate the clinical effect of different administration of sufentanil through nose and vein during fiberenteroscopy.Methods The clinical data of 62 patients admitted in our hospital in July 2016~July 2017 were divided into the control group and the study group,with 31 cases in each group.The control group was treated with sufentanil intravenous administration,the study group was treated with sufentanil nasal drops,and the two groups of life indexes and clinical indexes were analyzed.Results The heart rate and MAP of the study group were lower than those of the control group,SpO2 was higher than that of the control group,the difference was statistically significant(P<0.05),and the clinical index of the study group was superior to that of the control group,with a statistically significant difference(P<0.05).Conclusion When fiber colonoscopy is used for examination,the clinical effect of sufentanil through nose is better,the vital signs of patients are stable,and the drug has a weak respiratory inhibition function,so it has the value of clinical promotion.