噬菌体与宿主细菌的攻防机制

Defense and Anti-defense Mechanisms of Bacteriophages and Host Bacteria

噬菌体是侵袭细菌的病毒,也是病毒中最普遍、分布最广的类群。为了防止噬菌体侵染,细菌进化出多种多样的防御机制;而为了突破这些防御机制,噬菌体也进化得到了相对应的反制策略。本文即综述了这一领域的研究进展,有助于理解噬菌体与宿主细菌的共存共进化机制,合理利用噬菌体。

Bacteriophage,the virus of bacteria,is the world’s largest and most abundant organism of virus.On one hand,bacteria have developed various defense mechanisms to prevent phage infection,and on the other hand,phages have also evolved corresponding countermeasures to break through these defense mechanisms.In this paper,the research progress in this field was reviewed to understand the co-evolution mechanism between phage and host bacteria,so as to facilitate the rational use of phage.