宫颈癌盆腔淋巴结转移分布及危险因素分析

Distribution and Risk Factors of Pelvic Lymph Node Metastasis in Cervical Cancer

目的分析贵州地区宫颈癌淋巴结转移的临床病理特点。方法收集2010年2月~2014年7月我院收治的ⅠB~ⅡB期168例宫颈癌手术患者临床病理资料,回顾性分析淋巴结分布情况及相关高危因素及预后。结果淋巴结转移部位差异有统计学意义(P<0.05),闭孔淋巴结最易出现转移,淋巴结转移与FIGO分期、脉管癌栓/神经侵犯、宫旁浸润、病理分化程度、肌层浸润深度均有关,与病理类型及年龄无关。淋巴结转移组预后较非转移组差。结论宫颈癌淋巴结分布以顺站转移为主,分期、脉管癌栓/神经侵犯、宫旁浸润、病理分化程度、肌层浸润深度是淋巴结转移危险因素,淋巴结转移者预后差于无转移者。

Objective To analyze the clinicopathological features of cervical lymph node metastasis in Guizhou province.Methods The clinical and pathological data of 168 patients with stageⅠB~ⅡB cervical cancer admitted to our hospital from February 2010 to July 2014 were retrospectively analyzed.The distribution of lymph nodes and related risk factors and prognosis were retrospectively analyzed.Results There were significant differences in lymph node metastasis between the two groups(P<0.05).Most of the closed-cell lymph node metastases,lymph node metastasis and FIGO staging,vascular tumor thrombosis/nerve invasion,uterine infiltration,pathological differentiation,depth of myometrial invasion related.Has nothing to do with the pathological type and age.The prognosis of lymph node metastasis group was worse than that of non-metastasis group.Conclusion The distribution of lymph nodes in cervical cancer was mainly in the same station,stage,vascular tumor embolus/nerve invasion,periuterine infiltration,pathological differentiation,depth of myometrium invasion were risk factors of lymph node metastasis.The prognosis of lymph node metastasis was worse than that of non-metastasis.