降钙素原对新生儿感染性肺炎的早期诊断价值研究

Study on the Value of Procalcitonin in the Early Diagnosis of Neonatal Infectious Pneumonia

目的观察PCT在早期诊断新生儿感染性肺炎中的作用,评价其临床应用价值。方法选择2016年7月~2017年7月在我院接受治疗的62例感染性肺炎新生儿设为肺炎组,选择同期于我院出生的60例健康新生儿设为健康组,均展开PCT检测,对比分析检测结果。结果肺炎组新生儿PCT水平高于健康组新生儿,且肺炎组PCT阳性检出率(98.39%)高于健康组(3.33%),差异有统计学意义(P<0.05);细菌性肺炎患儿PCT阳性检出率为95.24%,高于支原体肺炎患儿PCT阳性检出率(80.00%)及病毒性肺炎患儿PCT阳性检出率(79.17%),差异有统计学意义(P<0.05);治疗后,病毒性、支原体、细菌性肺炎患儿的PCT水平及阳性检出率均有所下降,治疗前后比较差异有统计学意义(P<0.05)。结论在感染性肺炎新生儿中,PCT有较高敏感性,展开检测可促进早期确诊率的提升,并对不同类型的肺炎进行明确,以便于尽早干预治疗。

Objective To observe the role of PCT in the early diagnosis of neonatal infectious pneumonia,evaluation of its clinical application value.Methods 62 neonates with infectious pneumonia received treatment in our hospital from July 2016 to July 2017 were selected as pneumonia group.60 healthy newborns born in our hospital at the same time were selected as the healthy group.The PCT test was carried out and the results were compared and analyzed.Results The level of PCT in pneumonia group was higher than that in healthy group,and the positive rate of PCT in pneumonia group was(98.39%)higher than that in healthy group(3.33%),the difference was statistically significant(P<0.05).The positive rate of PCT in children with bacterial pneumonia was 95.24%.PCT positive rate in children with mycoplasma pneumonia(80.00%)and PCT positive rate in children with viral pneumonia(79.17%),the difference was statistically significant(P<0.05).After treatment,the PCT level and positive rate of children with viral,mycoplasma and bacterial pneumonia decreased,the difference before and after treatment was statistically significant(P<0.05).Conclusion PCT has a high sensitivity in neonates with infectious pneumonia,and it can promote the early diagnosis rate.Different types of pneumonia were identified to facilitate early intervention and treatment.