男性吸烟与骨密度及骨生化指标关系的调查与分析

Investigation and Analysis of the Relationship between Male Smoking and Bone Mineral Density and Bone Biochemical Index

目的研究男性吸烟与骨密度及骨生化指标关系的调查与分析。方法选择2012年1月~2016年1月某社区的500例吸烟男性为观察组,另外选择500例不吸烟的男性作为对照组,比较两组研究对象的骨代谢及骨生化指标,分析吸烟对上述两种因素造成的影响。结果观察组各部位骨密度均显著低于对照组(P<0.05),观察组sBAP和年龄明显高于对照组(P<0.05),但25-羟基总维生素D则显著低于对照组(P<0.05),差异有统计学意义。结论男性随着年龄的增长骨量会逐渐丢失,而吸烟会造成男性骨生化指标和骨转换水平升高,加速骨量的丢失,所以吸烟是造成骨质疏松的危险因素之一,要预防骨质疏松的发生应当提倡戒烟。

Objective To investigate the relationship between male smoking and bone mineral density and bone biochemical markers.Methods 500 smokers from January 2012 to January 2016 in a community were selected as the observation group.Another 500 nonsmokers were selected as the control group.The bone metabolism and bone biochemical indexes of the two groups were compared,analysis of the impact of smoking on these two factors.Results The observation group BMD were significantly lower than the control group(<0.05),the observation group sBAP and age was significantly higher than the control group(<0.05),but the total 25-hydroxy vitamin D was significantly lower than the control group(<0.05),the difference was statistically significant.Conclusion With the increase of bone age of the male will gradually lost,and smoking will result in increased male bone biochemical markers and bone turnover level,accelerated loss of bone mass,so smoking is one of the risk factors causing osteoporosis,to prevent osteoporosis should give up smoking.