期刊文献+

126例甲状腺乳头状癌临床病理分析

原文传递
导出
摘要 目的 总结分析甲状腺乳头状癌的临床病理特征。方法 收集126例甲状腺乳头状癌的病理资料,光镜下观察术中冰冻切片及常规石蜡切片,并对其中9例行免疫组织化学CK19、Galectin-3、MC、CK34βE12、CD57及Ki67标记。结果 126例患者包括女性102例,男性24例,经术中冰冻诊断确诊108例,准确率为85.7%。延迟诊断15例(11.9%),假阴性诊断3例(2.4%)。免疫组织化学标记物CK19和Galectin-3在甲状腺乳头状癌中强阳性表达。结论 甲状腺乳头状癌女性多见,术中冰冻切片对甲状腺乳头状癌的诊断具有重要应用价值,病理医师需掌握冰冻切片中组织结构及细胞形态的变异,以提高诊断的准确性,CK19和Galectin-3有助于甲状腺乳头状癌的诊断。
作者 娄艳芳
出处 《医学新知》 CAS 2018年第A01期315-316,共2页 New Medicine
  • 相关文献

参考文献1

二级参考文献40

  • 1卢崇亮,张显岚.甲状腺结节的诊治进展[J].中国普通外科杂志,2006,15(4):282-285. 被引量:14
  • 2Pazaitou-panayiotou K, Capezzone M, Pacini F. Clinical features and therapeutic implication of papillary thyroid microcarcinoma[J]. Thyroid, 2007, 17(11):1085-1092.
  • 3J'eon SI, Kim E, Park JS, et al. Diagnostic benefit of thyroglobulin measurement in fine-needle aspiration for diagnosing metastatic cervical lymph nodes from papillary thyroid cancer: correlations with US features[J]. Korean J Radiol, 2009, 10(2):106-111.
  • 4Pelizzo MR, Boschin IM, Toniato A, et al. Papillary thyroid microcarcinoma(PTMC): prognostic factors, management and outcome in 403 patients[J]. Eur J Surg Oncol, 2006, 32(10): 1144-1148.
  • 5Piersanfi M, Ezzat S, Asa SL. Controversies in papillary microcarcinoma of the thyroid[J]. Endocr Pathol, 2003, 14(3): 183-191.
  • 6Baudin E, Travagli JP, Ropers J, et al. Microcarcinoma of the thyroid gland : the Gustave-Roussy Institute experience[J]. Cancer, 1998, 83(3):553-559.
  • 7Noguchi S, Yamashita H, Murakami N, et al. Small carcinomas of the thyroid.A long-term follow-up of 867 patients[J]. Arch Surg,1996, 131(2):187-191.
  • 8Hay ID, Grant CS, van Heerden JA, et al. Papillary thyroid microcarcinoma:a study of 535 cases observed in a 50-year period[J]. Surgery, 1992, 112(10):1139-1147.
  • 9Lang W, Borrusch H, Bauer L, et al. Occult carcinoma of the thyroid. Evaluation of 1020 sequential autopsies[J]. Am J Clin Pathol, 1988, 90(1):72-76.
  • 10Sugitani I, Fuminoto Y. Symptomatic versus asymptomatic papillarythyroid microcarcinoma: a retrospective analysis of surgical outcome and prognostic factors[J]. Endocr J, 1999, 46(1):209-216.

共引文献36

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部