美托洛尔与阿托伐他汀治疗老年不稳定心绞痛的效果观察

Effect observation of metoprolol and atorvastatin on the elderly patients with unstable angina pectoris

目的:探讨美托洛尔与阿托伐他汀治疗老年不稳定心绞痛的临床疗效。方法:收治老年不稳定心绞痛患者36例,随机分为两组。对照组给予阿托伐他汀治疗,试验组给予美托洛尔和阿托伐他汀联合治疗,比较两组临床疗效、心绞痛发作情况以及心功能指标。结果:试验组总有效率94.44%,对照组总有效率55.56%,试验组总有效率高于对照组,差异有统计学意义(P<0.05)。与试验组相比,对照组心绞痛发作时间较长、发作频率较高,SV值和EF值较低,差异有统计学意义(P<0.05)。结论:美托洛尔和阿托伐他汀联合治疗老年不稳定心绞痛患者的临床疗效显著,可明显改善患者的心绞痛情况。

Objective:To investigate the clinical effect of metoprolol and atorvastatin in the treatment of elderly patients with unstable angina pectoris.Methods:36 cases of elderly patients with unstable angina pectoris were divided into two groups randomly.The control group was treated with atorvastatin,and the experiment group was treated with metoprolol and atorvastatin.The clinical effect,angina pectoris and cardiac function were compared between groups.Results:The total effective rate of the experiment group was 94.44%,and the total effective rate of the control group was 55.56%.The total effective rate of the experiment group was higher than that of the control group,and the difference was statistically significant(P<0.05).Compared with the experiment group,the control group had longer attack time,higher seizure frequency,lower SV value and EF value,and the difference was statistically significant(P<0.05).Conclusion:Metoprolol combined with atorvastatin in the treatment of elderly patients with unstable angina pectoris had significant clinical effect,and could improve the angina pectoris significantly.