氨溴索在哮喘性支气管炎治疗中的应用效果及安全性评价

Efficacy and Safety Evaluation of Ambroxol in the Treatment of Asthmatic Bronchitis

目的探讨氨溴索在哮喘性支气管炎治疗中的应用效果及安全性。方法选取2016年1月~2017年1月在我院就诊的哮喘性支气管炎患者130例进行研究,按照患者入院时间奇偶数将患者分为两组,每组65例,对照组采用常规治疗,观察组采用氨溴索治疗,对两组治疗效果及FEV_1、FEV_1/FVC、不良反应情况进行对比。结果观察组患者总有效率为95.38%高于对照组为80.00%,差异有统计学意义(P<0.05);治疗后,观察组FEV_1(1.8±0.4)L、FEV_1/FVC(66.7±8.7)%,优于对照组(1.6±0.3)L、(56.9±6.3)%,差异有统计学意义(P<0.05)。结论采用氨溴索对哮喘性支气管炎患者进行治疗效果显著,有利于改善患者肺功能,且具有较高的安全性,可在临床上推广应用。

Objective To investigate the effect and safety of ambroxol in the treatment of asthmatic bronchitis.Methods From January 2016~2017 year in January in our hospital 130 cases of patients with asthmatic bronchitis were studied,according to the time of admission in patients with odd and even method,patients were divided into two groups,65 cases in each group,the control group received routine treatment,observation group were treated with ambroxol treatment,compared two groups of treatment and FEV1,FEV1/FVC,adverse reaction the situation.Results In the observation group,the total efficiency is 95.38%higher than that of control group was 80.00%,the difference was statistically significant(<0.05);after treatment,the observation group FEV1(1.8依0.4)L,FEV1/FVC(66.7依8.7)%,better than the control group(1.6依0.3)L,(56.9依6.3)%,with statistical significance the difference(<0.05).Conclusion Ambroxol is effective in the treatment of asthmatic bronchitis.It is beneficial to improve the lung function of patients,and has high safety.It can be widely applied in clinic.