临床实践指南制订方法——证据的检索及评价

Methodology for clinical practice guidelines——Evidence Searching and Evaluation

证据的检索及评价是指南制订的重要步骤,全面、客观、可重复的文献检索是指南制作过程中最耗时、最具挑战性及最重要的工作,敏感的检索策略和多样的检索资源是减少文献查找偏倚的关键,也是制订系统评价并最终形成推荐意见的基础。此过程中常常需要优化检索策略、确定检索资源及依靠方法质量学评价进行文献的筛选与最终确定。

The systematic identification of evidence is an essential step in developing guidelines.A comprehensive,objective,and repeatable literature search is the most time-consuming,challenging,and important task in the developing guidelines.Sensitive search strategies and multiple search resources are key to reduce bias.It is a process that often include constructing key questions,determining search resources,and assessing methodological quality.According to the different problems that need to be solved,searching different types of research and evaluating related documents are the basis for formulating systematic reviews and eventually forming recommendations.