乳腺癌新辅助化疗的研究概况

Research progress of neoadjuvant chemotherapy for breast cancer

新辅助化疗(neoadjuvant chemotherapy,NCT)是在乳腺癌局部治疗前进行的一种全身化学药物治疗。临床研究显示,NCT对提高保乳率、降低临床分期、指导化疗方案的选择、防止远处转移、提高病理完全缓解率等方面具有一定的作用,但也存在不少有待解决的问题。该文就乳腺癌NCT的研究概况作一综述。

Neoadjuvant chemotherapy(NCT)is a systemic chemotherapy before local treatment of breast cancer.Clinical studies have shown that NCTs have a certain effect on improving breast-conserving rate,clinical downstaging,guiding the choice of chemotherapy regimens,preventing distant metastasis and improving the pathological complete remission rate.However,there are also many problems remaining to be solved.In this paper,we review the research progress of neoadjuvant chemotherapy for breast cancer.