皮层下动脉硬化性脑病的睡眠呼吸监测32例临床分析

Screening obstructive sleep apnea-hypopnea syndrome in subcortical atherosclerotic encephalopathy by polysomnography

目的 研究皮层下动脉硬化性脑病患者的睡眠呼吸特点。方法 纳入32例明确诊断为皮层下动脉硬化性脑病患者,同时纳入年龄和性别匹配的正常人为对照。两组均进行夜间睡眠呼吸监测。结果 皮层下动脉硬化性脑病组AHI指数12.8(4.3~31.3),动脉血氧饱和度<90%的比例4.3%(0.8%~13.2%),呼吸相关微觉醒指数4.5(0.5~11.2),均显著高于对照组(均P<0.05)。皮层下动脉硬化性脑病组睡眠时间(6.7±2.0)h,氧减指数4.0(1.6~5.4),和对照组相比差异无统计学意义(P>0.05)。对照组AHI指数2.8(0.8~4.9),两组相比差异有统计学意义(P<0.001)。结论 皮层下动脉硬化性脑病患者发生睡眠呼吸暂停比率高,值得引起临床重视。

Objective To screen the prevalence of obstructive sleep apnea-hypopnea syndrome in patients with subcortical atherosclerotic encephalopathy.Mehtods Thirty two patients with subcortical atherosclerotic encephalopathy and 32 sex-and age-matched normal adults were included into this study.All the subjects were evaluated by polysomnography.Results Compared with the normal controls,the patients with subcortical atherosclerotic encephalopathy had a higher AHI index,a higher percentage of O2 saturation lower than 90%,and a higher respiratory event related microarousal index(all P<0.05).The total sleep time and oxyhemoglobin desaturation index were comparable between the two groups(P>0.05).Conclusion Patients with subcortical atherosclerotic encephalopathy are highly susceptible to obstructive sleep apnea-hypopnea syndrome.