温州地区绝经后老年女性骨质疏松的患病率及其危险因素分析

The prevalence and risk factors analysis of osteoporosis among Wenzhou postmenopausal women

目的调查温州地区绝经后老年女性骨质疏松的患病率及其危险因素,为社区绝经后老年女性骨质疏松防治提供理论依据。方法选择温州医科大学附属第二医院体检老年女性1 079例,收集体格检查、体成分测量和血生化指标等资料,采用双能X线(DEXA)进行骨密度测量。采用logistic回归分析骨质疏松与相关因素之间的关系。结果温州地区绝经后老年女性骨质疏松患病率为37.53%。Logistic回归分析显示,年龄、钙的摄入量低、维生素D3浓度缺乏、骨质疏松家族史、高血压、糖尿病史是绝经后老年女性骨质疏松的危险因素(OR分别=2.19、1.93、2.34、1.74、1.04、1.95,P均<0.05);肌力水平、超重或肥胖是绝经后老年女性骨质疏松的保护因素(OR分别=0.58、0.40、0.27,P均<0.05)。结论绝经后老年女性骨质疏松发病率较高,与年龄、钙的摄入、BMI、维生素D3含量、肌力水平、糖尿病患病情况、骨质疏松家族史等多种因素密切相关。

Objective To investigate the prevalence and risk factors of osteoporosis in postmenopausal women in Wenzhou,and to provide a theoretical basis for the prevention and treatment of osteoporosis in the elderly postmenopausal women in the community.Methods Totally 1079 aged women were selected from the second affiliated hospital of Wenzhou medical university.The data of physical examination,body composition measurement and blood biochemical indexes were collected,and bone mineral density was measured by double energy X-ray(DEXA).Logistic regression analysis was used to analyze the relationship between osteoporosis and related factors.Results The prevalence of osteoporosis in postmenopausal elderly women in Wenzhou was 37.53%.Logistic regression analysis showed that age,low calcium intake,lack of vitamin D3,family history of osteoporosis,hypertension,and diabetes history were risk factors for osteoporosis in postmenopausal women(OR=2.19,1.93,2.34,1.74,1.04,1.95,P<0.05),and the level of muscle strength,overweight or obesity were the protective factors(OR=0.58,0.40,0.27,P<0.05).Conclusion The incidence of osteoporosis in postmenopausal women is high,which is closely related to age,calcium intake,BMI,vitamin D3 concentration,muscle strength,diabetes prevalence,family history of osteoporosis and so on.