胃癌术后辅助化疗的研究进展

Research progress in postoperative adjuvant chemotherapy of gastric cancer

胃癌术后辅助化疗是改善患者预后的重要方法。术后辅助化疗的作用已被明确,但目前在首选术后辅助方案上仍未达成统一的全球共识。尽管治疗方案因地区而异,但各种推荐辅助化疗方案在改善生存率上均存在有力的证据。为此,多年来人们一直在探索其合适治疗人群和最佳化疗方案,各国开展的多项研究基本证实了术后辅助化疗的作用并对比不同术后化疗方案的生存获益情况,本文将对胃癌术后辅助治疗的现状及研究进展作一综述。

Postoperative adjuvant chemotherapy of gastric cancer plays an important role in improving the prognosis.The role of postoperative adjuvant chemotherapy has been identified.However,there is no consensus on the choice of postoperative adjuvant protocols.Treatment options vary from region to region,but there is strong evidence for various recommended adjuvant chemotherapy regimens in improving patient survival.Investigators from various countries have been exploring over years in order to find the appropriate patients to be treated and the most beneficial chemotherapy regimes.They conducted a number of studies which had confirmed the role of postoperative adjuvant chemotherapy and compared the benefit of different chemotherapies.This review introduces the current situation and progress in the postoperative adjuvant chemotherapy of gastric cancer.