口腔疣状癌临床诊治的研究进展

Research Progress in Clinical Diagnosis and Treatment of Oral Verrucous Carcinoma

口腔疣状癌(oral verrucous carcinoma,OVC)是一种具有独特组织学改变和生物学行为的恶性肿瘤。临床上常表现为缓慢增大,灰白色的疣状增生物,主要好发于上、下颌牙龈及其附近黏膜皱褶处。本文从口腔疣状癌的病因、临床表现和分型、病理学表现、诊断和鉴别诊断、治疗和随访等方面的研究进展作一述评。

Oral verrucous carcinoma(OVC),a malignant tumor,has distinctive and unique histological changes and biological behaviors.The clinical manifestations of OVC often appear as a slowly increasing verrucous offwhite growth,which primarily occurs in the maxillary and mandibular gums and in the nearby mucosal folds.In this review,we focused on the research progress and gave insight into the etiology,clinical manifestation and classification,oral pathology,diagnosis and differential diagnosis,treatment,and follow-up of oral verrucous carcinoma,so as to serve as a spur to stimulate more worthy and valuable contributions.