米索前列醇联合硫酸镁治疗妊娠高血压综合征产后出血的效果观察及价值探讨

Effect and Value of Misoprostol Combined with Magnesium Sulfate in the Treatment of Postpartum Hemorrhage in Pregnancy-induced Hypertension Syndrome

目的探讨米索前列醇联合硫酸镁治疗妊娠高血压综合征产后出血的效果观察及价值。方法选取本院2015年9月~2017年4月收治的66例妊娠高血压综合征产后出血患者作为研究对象,按照随机数字表法分为对照组和实验组,每组33例,对照组予以催产素联合硫酸镁进行治疗,实验组予以米索前列醇联合硫酸镁进行治疗,观察并比较两组临床疗效和止血效果。结果两组治疗后SBP、DBP均明显低于治疗前,组间展开对比,实验组均低于对照组(P<0.05);实验组术后2 h、24 h出血量均明显少于对照组,组间差异具有统计学意义(P<0.05)。结论米索前列醇联合硫酸镁治疗妊娠高血压综合征产后出血效果显著,有利于尽快减少和控制产后出血,值得临床借鉴和选择。

Objective To investigate the effect and value of misoprostol combined with magnesium sulfate in the treatment of postpartum hemorrhage in pregnancy-induced hypertension.Methods Sixty-six patients with postpartum hemorrhage due to pregnancy-induced hypertension were enrolled in our hospital from September 2015 to April 2017.They were divided into a control group and an experimental group according to the random number table method.There were 33 cases in each group.Oxytocin was combined with magnesium sulfate for treatment.The experimental group was treated with misoprostol combined with magnesium sulfate.The clinical efficacy and hemostatic effect of the two groups were observed and compared.Results After treatment,SBP and DBP were significantly lower in the two groups than before treatment.The comparison between the two groups was performed.The experimental group was lower than the control group(P<0.05).The bleeding volume at the 2 h and 24 h after the operation was significantly lower in the experimental group than in the control group.There was a statistically significant difference between the two groups(P<0.05).Conclusion Misoprostol combined with magnesium sulfate is effective in the treatment of postpartum hemorrhage in pregnancyinduced hypertension syndrome,which is beneficial to reduce and control postpartum hemorrhage as soon as possible.It is worthy of clinical reference and selection.