术后抑郁症神经生物学及药物治疗的机制研究

Study on the neurobiology and medicine treatment of postoperative depression

分析讨论术后抑郁症神经生物学及药物治疗机制的研究进展。主要针对分子、基因、神经环路和神经影像学研究的进展进行了讨论。通过基因学、分子学、信号通路分子机制、神经元、神经环路和神经影像学的研究成果,更好的帮助理解抑郁症的神经生物学机制。分析了近几年主要抗抑郁药物的药理学研究和作用机制进展。

In this Seminar we discuss developments from the past years in the neurobiology,and treatment of postoperative depression.Advances in neurobiology have also increased,and we aim to indicate molecular,genetic,brain's circuitry and neuroimaging studies that are relevant for assessment and treatment selection of this disorder.Genetic,molecular,signal pathway's molecular mechanism,brain's circuitry and neuroimaging studies continue to advances in our understanding of the neurobiological basis of major depressive disorder.Further pharmacology studies and their mechanisms of action for six classes of antidepressants in recent years are also discussed.