连续肾脏替代疗法对治疗重症急性胰腺炎的临床效果及护理体会

The clinical effect and nursing experience of CRRT in treating severe acute pancreatitis

目的研究探讨连续肾脏替代疗法(continuous renal replacement therapy,CRRT)对治疗重症急性胰腺炎(sever acute pancreatitis,SAP)的临床效果及护理体会。方法将2016年1月至2017年1月青岛市市立医院收治的重症急性胰腺炎患者按照随机数表法各抽取60例患者分为观察组和对照组。两组患者均给予常规治疗,观察组患者在常规治疗的基础上给予CRRT治疗,治疗前后分别对两组患者的各项体征和指标进行检测记录,并进行统计学分析和比较。结果数据显示,导致SAP的致病因素中,首要的是暴饮暴食/高脂饮食,其次为饮酒,再者是胆源性疾病,不明原因导致疾病者较少;治疗前两组患者的实验室指标比较显示,两组患者的血钠、血钙、血钾、血尿素氮、血清肌酐、血白细胞计数、血小板计数、谷丙转氨酶、总胆红素等比较,差异均无明显统计学意义(P>0.05);治疗72小时后,两组比较,实验室指标均存在显著统计学意义(P<0.05);治疗72小时前后两组患者生命体征及尿量变化等数据比较显示,治疗前的两组数据之间不存在统计学意义(P>0.05);治疗72小时后两组患者的呼吸、心率及尿量比较,差异存在统计学意义(P<0.05)。结论 CRRT治疗重症急性胰腺炎效果显著,可明显改善患者各项生命体征和生化指标,对提高患者预后存在积极意义,值得在临床上进行广泛推广应用。

Objective To study the effect of CRRT on the treatment of severe acute pancreatitis and nursing experience.Methods The January 2016~2017 year in January in our hospital in patients with severe acute pancreatitis were divided into the implementation of continuous renal replacement therapy(CRRT)in CRRT group and conventional treatment group were randomly selected from the 60 patients were divided into observation group and control group,two groups of patients were given conventional treatment,observation patients in the conventional treatment based on the given continuous renal replacement therapy(CRRT)treatment,respectively before and after treatment in two groups of patients with various signs and indicators were detected and recorded,and statistical analysis.Results The data showed that the main cause of SAP was binge-eating/high-fat diet,followed by alcohol consumption,and choline disease,which caused less disease.In the two groups of patients,the comparison showed that the Na,Ca,K,BUN and SCr,WBC,PLT,ALT,TBIL were not statistically signifi cant(P>0.05).After treatment of 72小时,both groups showed signifi cant statistical signifi cance(P<0.05).Data comparison of the vital signs and urinary changes in the two groups before and after treatment of 72小时showed that there was no statistical signifi cance between the two groups of data before treatment(P>0.05).After treatment of 72 hours,the respiratory,heart rate and urine volume of the two groups were statistically signifi cant(P<0.05).Conclusion CRRT treatment of severe acute pancreatitis has a signifi cant effect,can signifi cantly improve the patient's vital signs and biochemical indicators,to improve the prognosis of patients with positive signifi cance,it is worthy of clinical application.