参苓白术散加减治疗结直肠癌术后泄泻临床效果观察

Clinical Effect Observation of Shenling Baizhu Decoction for the Treatment of Diarrhea after Colorectal Cancer Surgery

目的:观察参苓白术散加减治疗结直肠癌术后泄泻的临床效果。方法:选取72例结直肠癌术后泄泻患者作为研究对象,将其分为西医组与中西医组,每组36例,西医组应用蒙脱石散联合双歧杆菌三联活菌肠溶胶囊治疗,中西医组在西医组的基础上应用参苓白术散加减治疗,对比两组患者的临床疗效。结果:中西医组总有效率是94.4%,明显高于西医组的77.8%,差异有统计学意义(X2=4.181,P<0.05);中西医组的体温复常时间、呕吐缓解时间、腹痛缓解时间、大便正常时间均短于西医组,差异有统计学意义(t=10.733、14.056、16.100、7.785,P<0.05);中西医组的IL-6、TNF-α水平均低于西医组,差异有统计学意义(t=6.156、7.159,P<0.05)。结论:参苓白术散加减治疗结直肠癌术后泄泻的临床效果满意,可快速缓解临床症状,降低炎症因子水平,值得推行。

Objective:To observe the clinical effect of Shenling Baizhusan Decoction for the treatment of diarrhea after colorectal cancer surgery.Method:72 patients with diarrhea after colorectal cancer surgery were selected as the research object,they were divided into the western medicine group and the traditional Chinese medicine and western medicine group,36 cases in each group,the western medicine group received the treatment of Montmorillonite Powder combined with Bifid Triple Viable Capsules Dissolving at intestines,the traditional Chinese and western medicine group received treatment of Shenling Baizhu Decoction on the basis of the western medicine group,the clinical effect were compared between the two groups.Result:The total efficiency in the traditional chinese medicine and western medicine group was 94.4%,significantly higher than 77.8%in the control group(X^2=4.181,P<0.05).The Body temperature recovery time,vomiting remission time,abdominal pain relief time,normal defecation time in traditional chinese medicine and western medicine group were shorter than the western medicine group(t=10.733,14.056,16.100,7.785,P<0.05).IL-6 and TNF-levels in traditional chinese medicine and western medicine group were lower than the western medicine group(t=6.156,7.159,P<0.05).Conclusion:The clinical effect of Shenling Baizhu Decoction for the treatment of diarrhea after colorectal cancer surgery satisfaction,can quickly relieve symptoms,reduce the level of inflammatory factors,worth pursuing.