宫颈腺样基底细胞癌病变的病理诊断及特征分析

Clinicopathological Characteristics Analysis and Diagnosis of Adenoid Basal Carcinoma of the Uterine Cervix

目的分析宫颈腺样基底细胞癌病变的病理诊断及特征。方法回顾分析我院13例宫颈腺样基底细胞癌(ABC)病变患者临床资料,如病理形态学表现,结合免疫组织化学染色,分析患者的病理学特征。结果 13例宫颈ABC患者标本无切除检查,阴道镜检查无肉眼可见肿块。浸润深度0.18~1.42 cm,浸润宽度0.15~1.68 cm。患者均合并鳞状上皮内病变。部分患者无明显间质反应、其他患者的间质反应包含黏液样变性、疏松、水肿伴炎细胞3种。结论宫颈腺样基底细胞癌病变患者以绝经期中老年女性为主。这种疾病需在显微镜下得出准确诊断结果。宫颈ABC的临床诊断应与鳞状细胞癌、腺样囊性癌等病变作鉴别。

Objective In order to investigate the clinicopathologic features of cervical adenoid basal cell carcinoma.Methods 13 pathologic specimens were obtained from our hospital.The histopathologic diagnosis was reviewed.The immunohistochemistry was applied to detect the expression.Amalysised their clinicopathologic features.Results 13 cases of patients with adenoid basal carcinoma of the uterine cervix were not examined after surgery,and there were not no visible mass by colposcopy.The infiltrating depth of tumor ranged from 0..18-1.42 cm,and infiltrating width of tumor ranged from 0.15-1.68 cm,All patients were combined with squamous endothelial lesion,There was no significant interstitial response in some patients,The interstitial reactions of other patients included mucous degeneration,loose,edema,and inflammatory cells.Conclusion Adenoid basal carcinoma of cervix developed more at the middleaged and old women after menopause.The tumor is usually discovered as an incidental microscopic finding.Diagnosis of adenoid basal carcinoma of the uterine cervix should be clearly separated from squamous cell carcinoma,adenoid cystic carcinoma,and so on.