小剂量阿司匹林联合氯吡格雷治疗急性缺血性脑卒中的疗效观察

Effect of Low-dose Aspirin Combined with Clopidogrel on Acute Ischemic Stroke

目的观察小剂量阿司匹林联合氯吡格雷治疗急性缺血性脑卒中的临床治疗效果。方法选取我院2016年2月至2017年2月收治的98例急性缺血性脑卒中患者,按照随机分配原则将其分为对照组与实验组,每组患者各49例。对照组患者使用氯吡格雷治疗,实验组患者使用小剂量阿司匹林联合氯吡格雷治疗,观察并对比两组患者的治疗疗效。结果实验组患者的治疗有效率显著高于对照组,P<0.05,差异具有统计学意义;两组患者在治疗的不良反应的比较上无明显差异,P>0.05,不具有统计学意义。结论在急性缺血性脑卒中患者的治疗过程中,小剂量阿司匹林联合氯吡格雷能够有效缓解患者的各项指标及临床症状,临床治疗效果显著,不良反应明显减少,值得在临床上推广应用。

Objective To observe the clinical effect of low-dose aspirin combined with clopidogrel in the treatment of acute ischemic stroke.Methods 98 patients with acute ischemic stroke admitted in our hospital from February 2016 to February 2017 were divided into control group and experimental group according to the principle of random distribution,among which 49 cases were each group.In the control group,patients were treated with clopidogrel,and the patients in the experimental group were treated with low-dose aspirin and clopidogrel to observe and compare the therapeutic effects of the two groups.Results The effective rate of treatment in the experimental group was significantly higher than that in the control group(P<0.05).There was no significant difference between the two groups in the treatment of adverse reactions(P>0.05),which was not statistically significant.Conclusion Low-dose aspirin combined with clopidogrel can alleviate the indexes and clinical symptoms of patients with acute ischemic stroke.The clinical treatment effect is obvious and the adverse reaction is obviously reduced,which is worthy of clinical application.