冠脉介入治疗冠心病急性心肌梗死的临床疗效及对心室重塑影响

Clinical effect of percutaneous coronary intervention on acute myocardial infarction in patients with coronary heart disease and its effect on ventricular remodeling

目的观察冠脉介入治疗冠心病急性心肌梗死的临床疗效及对心室重塑的影响。方法收集2015年10月~2017年10月本院收治的82例冠心病急性心肌梗死患者,分研究组和对照组,每组41例。对照组采纳溶栓治疗,研究组采纳冠脉介入治疗。比较两组的血浆BNP值、心功能以及CK、CK-MB峰值。结果与对照第4天、第8天、第12天的血浆BNP值比较,研究组较低,差异有统计学意义(P<0.05);与对照组LVEF、LVEDD、LVESD指标比较,研究组较高,差异有统计学意义(P<0.05);研究组CK、CK-MB峰值高于对照组,差异有统计学意义(P<0.05)。结论冠脉介入治疗可有效改善冠心病急性心肌梗死血浆BNP水平,对心功能的良好转归具有促进作用,效果确切,值得借鉴。

Objective To observe the clinical efficacy of coronary intervention in the treatment of acute myocardial infarction(CHD)and its effect on ventricular remodeling.Methods From October 2015 to October 2017,82 patients with acute myocardial infarction were randomly divided into the study group and the control group,41 cases in each group.The control group received thrombolytic therapy,and the study group received coronary intervention.The plasma BNP,cardiac function and peak value of CK and CK-MB were compared between the two groups.Results Compared with the control group in fourth days,eighth days and twelfth days,the study group was lower,and the difference was statistically significant(P<0.05).Compared with the control group LVEF,LVEDD,LVESD index,the study group was higher,the difference was statistically significant(P<0.05).Compared with the peak value of CK and CK-MB in the control group,the study group was higher,the difference was higher.Statistical significance(P<0.05).Conclusion Coronary intervention can effectively improve the level of plasma BNP in acute myocardial infarction of coronary heart disease.It can promote the good prognosis of cardiac function,and it is effective and worthy of reference.