姑息性手术疗法在晚期胰腺癌患者治疗中的应用效果

Palliative surgery in patients with advanced pancreatic cancer treatment effect

目的探究对晚期胰腺癌患者实施姑息性手术疗法的效果。方法以本院110例晚期胰腺癌患者作为观察对象,对110例患者的临床资料进行回顾性分析,结合治疗方式的不同将其分为手术组(61例,应用姑息性手术疗法)、药物组(49例,应用常规化疗药物治疗),随访2年,研究对比手术组和药物组患者的疗效、生存情况及生存质量评分。结果手术组患者病变进展率相比药物组明显更低,且病变稳定率相比药物组明显更高(P<0.05);手术组患者6个月生存率、1年生存率及治疗后生存质量评分相比药物组明显更高,且平均生存时间相比药物组明显更长(P<0.05)。结论对晚期胰腺癌患者实施姑息性手术疗法的疗效更佳。

Objective To investigate the effect of palliative surgery on patients with advanced pancreatic cancer.Methods One hundred and ten patients with advanced pancreatic cancer in our hospital were observed.The clinical data of 110 patients were retrospectively analyzed.According to the different treatment methods,the patients were divided into operation group(61 cases,palliative surgery),drug group(49 cases treated with conventional chemotherapeutic drugs)were followed up for 2 years to compare the efficacy,survival and quality of life scores of the patients in the operation group and the drug group.Results The rate of lesion progression in the operation group was significantly lower than that in the drug group,and the stability of the lesion was significantly higher than that in the drug group(P<0.05).The 6-month survival rate,1-year survival rate and posttreatment quality of life score Was significantly higher than the drug group,and the average survival time was significantly longer than the drug group(P<0.05).Conclusion Palliative surgery is more effective for patients with advanced pancreatic cancer.