动态增强磁共振成像与直肠癌分化程度的相关性研究

Dynamic Contrast-enhanced MRI and Its Correlation With Rectal Cancer Differentiation

目的探讨动态增强磁共振成像与直肠癌分化程度的相关性。方法回顾性分析我院收治的50例直肠癌患者临床资料,术前均接受动态增强磁共振成像(DCE-MRI)诊断,术后行病理诊断,观察二者相关性。结果低分化腺癌11例,中分化腺癌32例,高分化腺癌7例;Kappa检验统计分析,证实患者术前MRI分期与病理分期结果一致性较高(P<0.01);Kruskal-Wallis秩和检验iACU值与分化程度成正相关关系(P<0.05)。结论动态增强磁共振成像与直肠癌病理分期及分化程度评估具有高相关性,可反映直肠癌微循环差异,价值显著。

Objective To investigate the correlation between dynamic contrast-enhanced magnetic resonance imaging and differentiation of rectal cancer.Methods The clinical data of 50 patients with rectal cancer treated in our hospital were analyzed retrospectively,and dynamic contrastenhanced magnetic resonance imaging(DCE-MRI)was performed before and after operation.Results There were 11 cases of poorly differentiated adenocarcinoma,32 cases of moderately differentiated adenocarcinoma and 7 cases of well-differentiated adenocarcinoma by Kappa test.It was proved that the correlation between preoperative MRI staging and pathological staging was higher(P<0.01)and the iACU value of Kruskal-Wallis rank sum test was positively correlated with the degree of differentiation(P<0.05).Conclusion Dynamic contrast-enhanced magnetic resonance imaging has a high correlation with pathological stage and differentiation degree of rectal cancer.It can reflect the difference of microcirculation in rectal cancer and has significant value.