纳洛酮联合醒脑静在院前急救一氧化碳中毒中的疗效评价

Clinical Evaluation of Naloxone Combined with Xingnaojing in Pre-hospital Emergency Carbon Monoxide Poisoning

目的:评价分析纳洛酮联合醒脑静在院前急救一氧化碳中毒中的疗效。方法:选取笔者所在医院2012年1月-2017年12月收治的一氧化碳中毒患者56例为对象进行研究,将其随机分为对照组和观察组,各28例。对照组采取常规急救措施,而观察组采取纳洛酮联合醒脑静实施院前急救。观察对比两组苏醒时间及抢救效果。结果:观察组苏醒时间(2.3±0.8)h,显著短于对照组的(3.8±2.2)h,差异有统计学意义(P<0.05)。观察组抢救总有效率为96.43%,显著高于对照组的75.00%,差异有统计学意义(P<0.05)。结论:在院前急救一氧化碳中毒患者的过程中采用纳洛酮联合醒脑静疗效显著,且可显著缩短患者的苏醒时间,因此值得临床应用推广。

Objective:To evaluate the efficacy of Naloxone combined with Xingnaojing in pre-hospital emergency carbon monoxide poisoning.Method:Fifty-six patients with carbon monoxide poisoning who were admitted to our hospital from January 2012 to December 2017 were selected for study.They were randomly divided into control group and observation group,with 28 cases in each group.The control group took conventional first-aid measures,while the observation group took Naloxone and Xingnaojing to perform pre-hospital care.Observed and compared the recovery time and rescue effect of the two groups.Result:The awakening time of(2.3±0.8)h in the observation group was significantly shorter than(3.8±2.2)h in the control group,and the difference between two groups was statistically significant(P<0.05).The total effective rate of rescue in the observation group was 96.43%,highter than 75.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion:The use of Naloxone combined with Xingnaojing in the treatment of patients with carbon monoxide poisoning in pre-hospital is very effective and can significantly shorten the awakening time of patients.Therefore,it is worthy of clinical application.