浓缩生长因子联合骨代用品在上颌前牙区拔牙位点保存中的临床应用

Clinical Application of Concentrated Growth Factor Combined with Bone Substitute in the Extraction of Maxillary Anterior Region

目的:探究浓缩生长因子联合骨代用品在上颌前牙区拔牙位点保存中的效果,为临床提供指导。方法:以2015年1月10日-2016年12月20日在笔者所在医院行上颌前牙区拔牙48例患者作为观察对象并随机分组,每组24例。试验组患者应用浓缩生长因子联合骨代用品干预,对照组患者未实施干预,均随访6个月,研究对比两组患者拔牙位点唇、腭侧骨板高度和牙槽嵴宽度。结果:试验组患者术后6个月唇侧骨板高度(19.10±1.65)mm、腭侧骨板高度(17.65±2.14)mm、牙槽嵴宽度(7.10±0.90)mm,均优于对照组的(14.80±1.35)、(15.78±1.64)、(5.12±0.95)mm,差异均有统计学意义(P<0.05)。结论:在上颌前牙区拔牙位点保存中应用浓缩生长因子联合骨代用品具有较好的效果,可有效维持唇、腭侧骨板高度和牙槽嵴宽度。

Objective:To explore the effect of Concentrated Growth Factor combined with bone substitute in the preservation of extraction sites in maxillary anterior teeth.Method:A total of 48 cases of extraction of maxillary anterior teeth in our hospital from January 10th,2015 to December 20th 2016 were selected as the subjects and randomly divided into two groups,24 cases in each group.The experimental group was treated with Concentrated Growth Factor and bone substitute,while the control group did not take intervention.All cases were followed up for 6 months.The height of extraction tooth labial,palatal bone plate and the width of alveolar ridge of the two groups were compared.Result:The height of labial bone plate with(19.10±1.65)mm,palatal bone plate height with(17.65±2.14)mm and alveolar ridge width with(7.10±0.90)mm were significantly better in the experimental group than(14.80±1.35),(15.78±1.64),(5.12±0.95)mm in the control group,the differences were statistically significant(P<0.05).Conclusion:The application of Concentrated Growth Factor combined with bone substitute in the preservation of extraction sites of maxillary anterior teeth is effective in maintaining labial,palatal plate height and alveolar ridge width.