基于汉语高频名词下词图匹配语义判断任务的设计与运用范式

Design and Pilot Study of Word-picture Matching Semantic Judgment Task Based on Chinese High Frequency Nouns

目的探索基于汉语高频名词的词图匹配语义判断任务的设计思路,以及该任务下的功能磁共振成像(fMRI)和事件相关电位(ERP)实验研究方法,为该领域研究提供范式。方法阐述汉语高频名词的词图匹配判断任务的材料来源和设计流程,并纳入1例健康受试者,进行词图匹配语义判断任务下的f MRI、ERP实验,将任务下采集的fMRI/ERP数据进行分析,判断该任务在fMRI/ERP实验中的可行性。结果 fMRI结果显示,与注视"+"时相比,受试者在词图呈现时右侧额中回激活增高;与词图匹配条件相比,受试者在词图不匹配条件下右侧颞中回激活增高。ERP结果显示,词图匹配条件下受试者左侧额颞区激活较明显,词图不匹配条件下右侧额叶区激活较明显。结论基于本实验设计,采用fMRI、ERP技术均可以获得语言相关脑区激活效应,提示本任务可用于探索汉语语言的脑加工机制。

Objective To explore the design of word-picture matching semantic judgment task based on Chinese high frequency nouns and further explore the way to apply the task in a functional magnetic resonance imaging(fMRI)/event-related potential(ERP)study.Methods The materials,stimuli and procedure of the word-picture matching semantic task were provided.Then,a healthy subject for the pilot study was included.In the pilot study,fMRI and ERP data of the subject were collected during the word-picture matching task.The fMRI and ERP data were analyzed to test the feasibility of the word-picture matching task in an fMRI/ERP task.Results The results of fMRI analysis showed an increased activity in the right middle frontal gyrus under the word-picture presenting condition compared with the"+"presenting condition.In addition,fMRI analysis showed an increased activity in the right middle temporal gyrus in the word-picture mismatching condition compared with the word-picture matching condition.The results of ERP analysis showed an increased activity in the left frontal/temporal area in the word-picture matching condition and an increased activity in the right frontal area in the word-picture mismatching condition.Conclusion Language associated brain regions can be identified in the fMRI/ERP research based on the word-picture matching task described in this article,which indicated that the task is effective in exploring language processing mechanism in the brain.