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羟考酮与舒芬太尼对老年胃癌根治术后的镇痛效果比较

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摘要 目的观察羟考酮对全麻下腹腔镜胃癌根治术老年患者苏醒质量的影响。方法选择2016年3月至2017年5月该院行腹腔镜胃癌根治术老年患者60例,随机分为羟考酮组与舒芬太尼组,各3 0例。关腹膜时羟考酮组予羟考酮0.1mg/kg,舒芬太尼组予舒芬太尼0.1μg/kg,两组入麻醉后监护室前启动镇痛泵行静脉自控镇痛,输注速率2ml/h,单次剂量0.5ml,锁定时间15分钟。分别于苏醒后5、10、30、60分钟采用数字疼痛强度量表(NRS)评估患者静息时切口及内脏痛情况,记录两组不良反应。结果各时间点两组皮肤切口痛NRS评分接近,差异无统计学意义(P>0.05)。各时间点内脏痛NRS评分羟考酮组明显低于舒芬太尼组;羟考酮组不良反应发生率(6.7%)明显低于舒芬太尼组(26.7%);差异有统计学意义(P<0.05)。结论羟考酮能有效减轻腹腔镜胃癌根治术老年患者术后内脏痛,降低不良反应发生率。
出处 《中国乡村医药》 2018年第13期11-12,共2页
基金 浙江省医药卫生科技计划项目(A类)(2016KY A179)
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