沙美特罗氟替卡松联合噻托溴铵对慢性阻塞性肺疾病临床疗效评价

Clinical Evaluation of Salmeterol and Fluticasone Propionate Combined With Tiotropium Bromide in the Treatment of Chronic Obstructive Pulmonary Disease

目的探究沙美特罗氟替卡松联合噻托溴铵对慢性阻塞性肺疾病临床疗效。方法选取本院2015年5月—2017年8月收治的60例慢性阻塞性肺疾病患者作为研究对象。按随机原则,将其分为对照组与研究组。对照组给予沙美特罗氟替卡松治疗,研究组给予沙美特罗氟替卡松联合噻托溴铵治疗。比较两组患者的治疗效果。结果两组患者肺功能指标以及6MWD比较,研究组优于对照组,差异均具有统计学意义(P<0.05)。结论对慢性阻塞性肺疾病患者进行沙美特罗氟替卡松联合噻托溴铵治疗效果显著,可以有效改善患者肺功能指标,患者6分步行距离也能得到增加。

Objective To explore the clinical efficacy of fluticasone combined with tiotropium bromide in the treatment of chronic obstructive pulmonary disease(COPD).Methods 60 patients with chronic obstructive pulmonary disease admitted in our hospital from May 2015 to August 2017 were selected as the research subjects.According to the principle of randomization,they were divided into control group and research group.The control group was treated with salmeterol and fluticasone.The study group was given salmeterol and fluticasone combined with tiotropium bromide.The therapeutic effects of the two groups were compared.Results The pulmonary function and 6MWD in the two groups were significantly different from those in the control group(P<0.05).Conclusion The effect of salmeterol and tiotropium on the patients with chronic obstructive pulmonary disease is significant.It can improve the pulmonary function of patients effectively,and the walking distance of 6min in patients can also be increased.