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酒后百草枯中毒1例护理体会

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摘要 百草枯为毒性很强的接触性除草剂,进入人体后随血液分布到各脏器,通过刺激腐蚀作用可引起多器官衰竭。急性百草枯中毒的主要靶器官为肺脏,急性肺泡炎和肺纤维化是主要表现,也是百草枯的重要死因。百草枯可经消化道、皮肤和呼吸道吸收,致死病例主要为自服或误服,成人致死量为20%水溶5~15ml(20~40mg/kg)[1]。乙醇是脂溶性助溶剂,通过刺激胃酸分泌、使细胞间隙加大等作用,导致胃黏膜充血、糜烂,减弱胃肠道屏蔽系统,加速百草枯吸收入血,加重胃肠道的腐蚀,导致胃肠道炎性因子大量吸收,进而加重百草枯中毒对全身各脏器的损害。
出处 《中国乡村医药》 2018年第15期70-71,共2页
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